Microneedling
Collagen Microneedling vs Microneedling + PDRN: Which Is Right for You?
October 8, 2026 · 5 min read · Medically reviewed by the Hayati clinical team
Microneedling is one of the most trusted ways to rebuild the skin from within. Adding PDRN, a regenerative ingredient derived from DNA fragments, takes the treatment a step further. Understanding what each does will help you choose with confidence.
Collagen microneedling
Using fine, sterile needles, microneedling creates controlled micro-channels in the skin. The body responds by producing new collagen and elastin, gradually firming and smoothing the treated area. It is a proven option for texture, enlarged pores, fine lines and shallow scarring.
What PDRN adds
PDRN (polydeoxyribonucleotide) is applied through the fresh micro-channels, where it supports the skin's natural repair processes. Guests often notice a calmer recovery and a more pronounced improvement in skin quality, hydration and overall vitality.
“Think of microneedling as the signal, and PDRN as the support that helps the skin answer it beautifully.”
How to choose
Both are excellent. Your choice depends on your goals and your skin's needs.
- Choose classic microneedling for texture and pore refinement
- Choose PDRN for sensitized, tired or recovering skin
- Choose PDRN for a stronger regenerative boost before an event season
Frequently Asked
Is microneedling painful?
A numbing cream is applied beforehand, so most guests feel only light pressure.
How many treatments do I need?
A series of three, spaced about four to six weeks apart, is typical for visible collagen remodeling.
When will I see results?
Skin looks fresher within a week, and collagen continues to build for months afterward.
Sources & Further Reading
- Microneedling can fade scars, uneven skin tone, and more (AAD)
- Acne scars: Consultation and treatment (AAD)
This article is for general education and is not a substitute for a personal medical consultation.
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